Posted On Dec 23, 2019
Manipal Hospitals
The skeleton is made up of bones, which provide support and shape to the body. They protect our internal organs from external injury. Together with the muscles, strong bones enable the body to move freely.
One of the most common bone-related problems that affect women is known as Osteoporosis. This is a condition where the bone density decreases, resulting in fragile bones. Osteoporosis leads to porous bones which are compressible. Therefore, a person suffering from osteoporosis is at a greater risk of fractured bones, especially in the hips, spine, wrists and ribs. In women, bone mass typically decreases after 35 years of age, and bone loss occurs more rapidly in women after menopause.
The factors that increase the risk of developing osteoporosis are:
• Reduced sex hormones: Lesser quantities of hormones, particularly, estrogen in case of women and androgen in the case of men, inhibit bone production.
• Age: The risk of osteoporosis is directly proportional to age, especially after the 30s and the post-menopausal period in women.
• Body structure: Being excessively thin or tall can increase the risk of osteoporosis.
• Genetic factors and family history: Having a close family member with a diagnosis of hip fracture due to osteoporosis doubles the risk of the person suffering from this condition. Other inherited disorders such as osteogenesis imperfections and skin diseases like Marfan syndrome may also be responsible.
• Alcohol and Tobacco: Excessive alcohol intake and smoking weaken the bone structure.
• Malnutrition: Low levels of essential nutrients such as calcium, magnesium and Vitamin D, can aggravate the risk of osteoporosis.
• Immobility: Being immobile for extended periods of time and not exercising regularly deprives your bones of vital movements needed to strengthen the bones and the joints.
• Hyperparathyroidism: It refers to a condition wherein the parathyroid gland produces excessive quantities of parathyroid hormone. This in turn causes too much calcium to be removed from the bones, weakening them.
• Medications: Long-term use of medicines such as heparin, which is a blood-thinner, anti-seizure medicines and oral corticosteroids such as prednisone can also cause osteoporosis.
• Gender and Ethnicity: Women are at a greater risk of developing osteoporosis than men, especially at later ages. Also, whites and Asians are more prone to this condition.
• Bone loss develops slowly and often there are no symptoms or signs of impending osteoporosis. A person may be unaware of it until he/she experiences a fracture due to an unrelated incident such as a fall or sometimes even a cough or sneeze.
• Back pain caused due to changes in the vertebrae is often the first sign.
• Pain in a particular location due to an osteoporotic fracture is a common symptom. A dull pain in the bones or muscles, especially low back pain or neck pain is also a symptom.
• Sudden onset of sharp pains that does not spread to other areas which lingers for a few months.
• A stooped posture resulting in a loss of height due to spinal fracture is a tell-tale sign of osteoporosis.
• Fractures at hips or wrist fractures due to a fall can sometimes reveal this condition.
The treatment for osteoporosis focuses on slowing down or preventing the development of this disease and aims to maintain a healthy bone mass and bone mineral density. It involves treating and preventing fractures, minimising the pain and maximising the person’s ability to carry on his/her daily activities. The treatment measures include:
Drugs: Biphosphonates are antiresorptive drugs that slow down the bone mass and reduce the risk of fractures. Biphosphonates may increase the risk of jaw bone destruction or cause gastrointestinal problems such as ulcers in the esophagus and acid reflux.