Growth hormone deficiency

In children, growth hormone deficiency symptoms include short stature, slower growth rate, and delayed puberty. In adults, symptoms may include reduced muscle mass, increased body fat, fatigue, decreased bone density, and impaired quality of life.

Growth hormone deficiency diagnosis requires a detailed clinical evaluation, including assessment of growth patterns and review of medical history. Blood tests are performed to measure hormone levels, followed by growth stimulation tests to confirm the deficiency. Imaging studies such as MRI of the pituitary gland help identify structural abnormalities and determine the underlying cause.

Growth hormone deficiency treatment primarily involves recombinant human growth hormone therapy, which is administered through regular injections. Treatment focuses on normalising growth in children and improving metabolic function, body composition, and overall well-being in affected individuals.

Patients with growth hormone deficiency at Manipal Hospitals undergo a comprehensive endocrine evaluation to confirm the diagnosis and determine its underlying cause. Specialists assess clinical features, growth patterns, and laboratory findings before deciding on the most suitable therapy.

Once the diagnosis is confirmed, treatment is individualised based on the patient’s age, severity of deficiency, and overall health status. Under medical supervision, doctors administer growth hormone therapy as daily subcutaneous injections. Regular follow-up visits are essential to monitor treatment response, adjust dosage, and assess for potential side effects.

For paediatric patients, treatment focuses on improving growth rate and helping achieve an appropriate height for age. In adults, therapy aims to improve metabolic health, increase bone density, and enhance overall well-being. Monitoring includes regular blood tests, growth assessment, and imaging when clinically indicated.

Understanding the growth hormone deficiency causes helps guide long-term management and identify associated conditions. With early diagnosis and consistent treatment, many patients experience significant improvements in growth outcomes and overall health.