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Dr. Parmod Mittal | Best Nephrologist in Delhi - Manipal Hospitals
Reviewed by

Dr. Parmod Mittal

Consultant - Nephrology

Manipal Hospitals, Delhi

10 Early Signs of Human Kidney Disease You Shouldn’t Ignore

Reviewed by:

Dr. Parmod Mittal

Posted On: May 12, 2025
blogs read 6 Min Read
10 Early Signs of Human Kidney Disease You Shouldn’t Ignore

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Your kidneys play a critical role in maintaining overall health, filtering blood, removing toxins, balancing fluids, regulating blood pressure, and aiding in red blood cell production. However, kidney disorders often develop silently. By the time you notice something is wrong, your kidneys might already be significantly compromised.

Chronic kidney disorders affect millions globally, and a large number of cases go undiagnosed in the early stages. This is primarily because the signs and symptoms of kidney disorder are subtle and easily confused with other health conditions. Early detection can make a huge difference in treatment outcomes, helping slow down or prevent irreversible damage.

In this article, we’ll explore the top 10 early kidney disorder symptoms that you should not ignore, along with health tips and when to seek expert care.

 

10 Early Kidney Disorder Symptoms

1. Persistent Fatigue

Feeling unusually tired despite getting enough rest? This can be an early sign of kidney dysfunction. When the kidneys are not working properly, they produce less erythropoietin, a hormone essential for red blood cell production. Low red blood cells result in anaemia, leading to constant fatigue and weakness, one of the most common signs and symptoms of kidney disorder.

2. Changes in Urination Patterns

Noticeable changes in how often or how much you urinate can signal kidney disorders. Look out for:

  • Frequent urination, especially at night

  • Foamy or bubbly urine (indicating protein leakage)

  • Blood in urine

  • Difficulty urinating

  • Reduced urine output or unusually pale/dark urine

Persistent changes warrant immediate evaluation.

3. Swelling in Feet, Ankles, or Hands

Swollen feet or ankles may indicate fluid retention caused by decreased kidney function. When kidneys can’t eliminate excess fluid properly, it accumulates in the body. Oedema — especially in the lower limbs — is one of the earlier visible kidney disorder symptoms.

4. Puffiness Around the Eyes

This is often due to protein leaking into the urine — a condition known as proteinuria. Puffy eyes, especially in the morning, are among the subtle yet important signs and symptoms of kidney disorder, particularly when accompanied by fatigue or weight loss.

5. Dry and Itchy Skin

The kidneys help maintain the body’s balance of minerals. When they're unable to filter waste, it can lead to mineral and bone disorders, reflected through dry, itchy skin. Chronic itching, especially without rashes, could signal deteriorating kidney health.

6. Shortness of Breath

If you’re frequently out of breath, even after minimal exertion, it may not just be a heart or lung issue. Kidney dysfunction can cause fluid build-up in the lungs or result in anaemia, both leading to breathlessness.

7. High Blood Pressure

High blood pressure is both a cause and a result of kidney disorders. Damaged kidneys are less effective at regulating blood pressure, which can accelerate damage in a vicious cycle. If you have recently developed hypertension, ask your doctor about kidney function tests.

8. Metallic Taste in the Mouth or Bad Breath

Toxins that are usually filtered out by healthy kidneys start to accumulate in the bloodstream in people with kidney problems. This can result in uraemia, causing a persistent metallic taste in the mouth and foul-smelling breath — a classic but often overlooked kidney disorder.

9. Muscle Cramps

An imbalance in electrolyte levels, such as calcium, phosphorus, and potassium, due to impaired kidney function, can trigger frequent and painful muscle cramps, especially in the legs.

10. Difficulty Concentrating

Toxin build-up due to kidney dysfunction may also affect brain function, causing problems with concentration, memory, and even mood changes. If you're often feeling mentally foggy or confused, and other symptoms exist, consider getting screened for kidney function.

10 Early Signs of Human Kidney Disease You Shouldn’t Ignore

Simple Tips to Protect Your Kidneys

Tip

Why It Matters

Stay hydrated

Helps kidneys flush out waste efficiently

Eat a low-salt, low-fat diet

Supports kidney and heart health

Control blood sugar and BP

Diabetes and hypertension are leading causes of kidney damage

Avoid overuse of painkillers

Long-term use of NSAIDs can harm kidney tissues

Exercise regularly

Improves blood circulation and keeps weight in check

Avoid smoking and limit alcohol

Both habits worsen kidney and cardiovascular health

Get regular checkups if high-risk

Early screening for diabetes, hypertension, or family history can save your kidneys

Who is at Risk of Kidney Disorders?

People with the following risk factors are more prone to developing kidney disorders:

  • Diabetes or high blood sugar

  • High blood pressure

  • Obesity or being overweight

  • A family history of kidney problems

  • Age above 60

  • History of recurrent UTIs or kidney stones

  • Long-term use of certain medications or herbal supplements

  • Smoking and a sedentary lifestyle

Don’t Ignore the Warning Signs – Seek Medical Help

If you notice any of the signs and symptoms of kidney disorder, even if they seem minor, it’s crucial to seek professional advice. Basic tests such as a urine analysis, serum creatinine levels, and glomerular filtration rate (GFR) can help detect early-stage kidney damage.

If you are in Delhi NCR and experiencing any symptoms of kidney disorders, Manipal Hospitals Dwarka provides world-class nephrology services. Backed by experienced nephrologists and the latest diagnostic technologies, the hospital offers:

  • Comprehensive kidney function testing

  • Dialysis and pre-dialysis care

  • Kidney transplant consultation and follow-up care

  • Personalised treatment plans for CKD, hypertension, and diabetes-related kidney conditions

Take charge of your kidney health today — schedule a consultation at Manipal Hospitals Dwarka for expert diagnosis and compassionate care.

Conclusion

Your kidneys may be quietly working behind the scenes, but their impact on your health is enormous. Recognising early kidney disorder symptoms — such as swelling, fatigue, foamy urine, and high blood pressure — can help catch problems before they escalate.

If you or your loved ones experience any of these symptoms, don't delay. Visit Manipal Hospitals Dwarka, where a specialised nephrologist provides services and expert medical teams are ready to support you on your journey to better kidney health. Early diagnosis and proactive care could be life-changing.

FAQ's

Early symptoms include fatigue, foamy urine, swelling in the ankles, and changes in urination patterns. These can often go unnoticed, so regular screening is essential.

While many kidney disorders are chronic and cannot be completely cured, early intervention and treatment can slow or even stop disease progression.

Yes. Persistent foamy urine is often a sign of protein leakage, which may indicate underlying kidney dysfunction.

If you have risk factors such as diabetes, hypertension, or a family history of kidney disease, annual testing is recommended.

Common tests include:

  • Urine test (for protein and blood)

  • Serum creatinine

  • eGFR (estimated Glomerular Filtration Rate)

  • Kidney ultrasound

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