Pharmacologic Measures, Such as Analgesics, Tricyclic Antidepressants and Anticonvulsants

Pharmacologic Measures treatment in Hebbal, Bangalore

Pharmacologic treatment in Hebbal, Bangalore have been proven to be effective in the treatment of chronic pain, especially neuropathic pain. Some medications have shown promising results in treating chronic pain. Some of these pharmacologic measures for relieving the pain have been discussed below,


Analgesics are a type of painkiller that helps treat different types of pain. This medicine provides ease to patients suffering from headaches to other injuries. It is also applied as anti-inflammatory medicine, considered effective in reducing inflammation. 

When are Analegics prescribed?

Analgesics are prescribed at the time of the following circumstances,

  • When your bone is injured

  • After the surgery

  • Injury in ankle

  • Headache

  • Menstrual cramps

  • Arthritis and back pain

Tricyclic Antidepressants

Tricyclic antidepressants are effective for the treatment of depression, and it shares the same chemical structure and biological effects. Tricyclic antidepressants help to bring balance between two neurotransmitters called norepinephrine and serotonin. The medicine helps to cure depression by keeping the neurotransmitters in balance.

Apart from treating depression, this medicine is also effective in reducing the chronic pain caused by migraine, headaches caused by tension, and pain due to post-herpetic neuralgia. 

When are Tricyclic Antidepressants used?

The food and Drug Administration (FDA) approves tricyclic antidepressants to treat depression. Apart from it, this drug is also used for the treatment of the following conditions,

  • Chronic pain

  • Panic disorder

  • Phantom limb pain

Differences Among Tricyclic Antidepressants

Depending on how they are used, tricyclic antidepressants may have different side effects and different effects on neurotransmitters. These antidepressants' effectiveness is also influenced by how long they stay in the body and by how well they interact with other drugs.

Some tricyclic antidepressants are Silenor, Anafranil, Pamelor, Sinequan, Norpramin, Vivactil, Asendin, Surmontil, and Vanatrip.


Anticonvulsants, commonly referred to as antiepileptics, are effective in treating chronic pain because they do so by obstructing sodium or calcium channels, which reduce pain. These are frequently employed to manage neuropathic pain in individuals. Antiepileptic medications are another name for anticonvulsants. One or more of the five mechanisms can be used by these medications to function.These mechanisms are,

  • Inhibition of sodium channel

  • Stimulation of neurotransmitters

  • Inhibition of calcium conductance

  • Inhibition of excitatory neurotransmitters

  • Combination with SV2A proteins

How do anticonvulsants work?

Anticonvulsant helps cure neuropathic pain caused by injury or problem in the central nervous system. When the central nervous system adapts to external stimuli, it is known as neuroplasticity which helps to maintain the pain symptom.

When are anticonvulsants used?

Anticonvulsants are used to treat the following conditions,

  • Epilepsies

Anticonvulsants are used to treat epilapsies. The presence of pharmacokinetics in the drugs helps treat epilepsies by giving complete freedom from seizures.

  • Prevent Migraines

Anticonvulsants also help to relieve the pain caused by migraines. 

  • Brain Disorder

Anticonvulsants are also helpful for treating some brain disorders, including bipolar disorder, borderline personality disorder, anxiety and other disorders.

These drugs work effectively by relieving the hyperactivity in the brain. These are also prescribed for people who are affected by mania and depression.

When Anticonvulsants are used to treat bipolar disorder, the drug contains

  • Tegretol

  • Valproic acid, divalproex sodium

  • Lamictal

Book an appointment at Manipal Hospitals to know more about treatments with the help of best doctors in Bangalore. 

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