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Dr. Srinivas K - Top Dentist in Old Airport Road, Bangalore - Manipal Hospitals
Reviewed by

Dr. Srinivas K

Consultant - Oral Physician & Dental Surgeon

Manipal Hospitals, Old Airport Road

Cure for Leukoplakia: Can White Patches in the Mouth Be Treated?

Reviewed by:

Dr. Srinivas K

Posted On: Apr 30, 2025
blogs read 5 Min Read
Cure for Leukoplakia: Can White Patches in the Mouth Be Treated?

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White, thick patches inside the mouth are typical signs of leukoplakia. These patches exist in 3 distinct areas of the mouth: the gums, the cheeks, and the floor, and they resist removal attempts. Research indicates that oral leukoplakia affects different populations, with studies demonstrating a variable prevalence ranging from 0.12% to 33.33%. In India, the prevalence of leukoplakia stands at 0.2% - 5.2%.

Leukoplakia has a potential cancer transformation rate between 0.1% and 17.5%. The critical nature of treating leukoplakia results from its ability to progress toward becoming oral cancer. So, is there a cure for leukoplakia? This blog looks into the elements triggering leukoplakia alongside its presenting features and available therapy methods.

 

What is Leukoplakia: Common Types

Leukoplakia is a condition in which thick white or greyish patches tend to develop on the mucous membranes inside the mouth. Most often, these patches occur due to chronic irritation or injury. Tobacco use, especially smokeless tobacco, and heavy alcohol consumption are significant risk factors for developing leukoplakia.

Leukoplakia can present in various types, each with its own characteristics. The most common types of Leukoplakia include:

  • Homogeneous Leukoplakia: This is the most common form, characterised by a uniformly white, flat, or slightly raised lesion.

  • Non-Homogeneous Leukoplakia: This type has a more varied appearance, including speckled, verrucous (wart-like), or red-and-white forms. It carries a higher risk of abnormal cell growth and malignant transformation.

  • Verrucous Leukoplakia: This specific type of non-homogeneous leukoplakia has a thick, white, wart-like appearance.

  • Erythroleukoplakia: This specific type has a mixed red and white appearance.

  • Proliferative Verrucous Leukoplakia (PVL): Often beginning as a small white patch, PVL is a rare but aggressive form that often spreads and recurs with a high potential for malignancy.

Symptoms of Leukoplakia

Leukoplakia typically presents as white or grey patches on the tongue, gums, or inside of the cheeks. These white patches in the mouth cannot be easily wiped or scraped away, which makes them different from other oral fungal infections like thrush (oral candidiasis). While many cases are benign, some can be precancerous with the potential to develop into oral cancer.

Cure for Leukoplakia: Can White Patches in the Mouth Be Treated?

Leukoplakia Causes: How to Diagnose the Disease?

Leukoplakia occurs due to a chronic inflammation in the mouth, most often caused by long-term irritation from the use of tobacco, alcohol, and betel nut (and paan). Sometimes, ill-fitting dentures, fillings, crowns, or cheek biting can also cause leukoplakia symptoms.

To diagnose leukoplakia, expert Oral Medicine specialist in Bangalore examine your mouth and order other tests based on your condition.

The diagnostic process may include:

  • Visual examination of the mouth

  • Medical history of the patient

  • Biopsy to check for precancerous and cancerous changes if leukoplakia is suspected

Is There a Cure for Leukoplakia?

Since the major cause of Leukoplakia remains irritants like tobacco or alcohol, addressing these issues with lifestyle changes is the first step towards treating the condition. Below are key points regarding the management of

  • Leukoplakia:

    • Medical Interventions: Surgical removal of lesions is often recommended, especially if abnormal cells are present.

    • Surgical Removal: Doctors may recommend surgically removing leukoplakic patches, especially if there's a cancer risk.

    • Medications: Topical Vitamin A, along with antioxidants, will be given to the patients.

  • Lifestyle Changes:

    • Quitting tobacco and limiting alcohol use can lead to the regression of leukoplakia lesions. However, it is not always easy to quit, and thus, considering support groups or rehab programs for quitting smoking and alcohol can be beneficial for patients with addiction to these substances.

    • Maintain Proper Oral Hygiene: Regular brushing and flossing help prevent infections and irritations that could lead to leukoplakia.

    • Regular Monitoring: Even after treatment, regular follow-ups with your dentist can help in the early detection and management of potential issues before they progress, and monitor for potential recurrence or malignant transformation.

  • Home Remedies:

    • Antioxidant Supplements: Daily supplements of beta-carotene, vitamin E, and vitamin C may help reduce leukoplakia lesions.

    • Turmeric Consumption: Curcumin in turmeric has shown promise in managing oral leukoplakia due to its anti-inflammatory properties.

Although these medical and home remedies can help manage the condition, it is always best to consult an experienced doctor to find a cure for Leukoplakia.

Conclusion

Leukoplakia presents as white or grey patches in the mouth, often linked to irritants like tobacco or alcohol. While treatments exist, prevention is paramount to reduce the risk of developing these potentially precancerous lesions. Implementing preventive measures can significantly reduce your risk of developing leukoplakia and promote overall oral health.

FAQ's

No, leukoplakia is not contagious. It develops due to chronic irritation, not an infection or virus.
 

Mild leukoplakia may sometimes disappear if the irritant (such as tobacco or alcohol) is removed. Therefore, regular check-ups are essential.
 

Leukoplakia patches are usually painless. However, discomfort may occur if they become irritated.
 

Stress alone does not cause leukoplakia, but it may contribute to habits like smoking, which increases the risk
 

A diet rich in antioxidants, like fruits and vegetables, may support oral health and reduce the risk of leukoplakia.
 

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