Workup of Thrombocytopenia

Workup of Thrombocytopenia in Yeshwanthpur, Bangalore


A low platelet count is known as thrombocytopenia. A platelet is a colourless blood cell that aids blood clotting. When blood vessels are injured, platelets clump and form plugs.

A bone marrow disorder such as leukaemia or an immune system problem can cause thrombocytopenia. Taking certain medications can also cause this side effect. The disease affects children as well as adults.

There are few signs or symptoms of thrombocytopenia, and it can be mild. There is a possibility of dangerous internal bleeding when the number of platelets is too low in the patient.

Workups for Thrombocytopenia

Most workups for thrombocytopenia do not follow an evidence-based algorithm and are not standardised. But, certain workups can be done based on test results, medical history and a physical examination. Workup of Thrombocytopenia in Yeshwanthpur, Bangalore is available at Manipal Hospitals.

Diagnostic Tests

The first step in the workup for thrombocytopenia is performing some blood diagnosis like CBC, Smear tests, Bone marrow tests, and other blood tests.


Complete blood counts (CBCs) measure your white blood cells, red blood cells, and platelet counts. A small amount of blood is taken from a blood vessel, usually in the arm, for this test. The results of this test will indicate a low platelet count if you suffer from thrombocytopenia.

Smear test

The appearance of your platelets is checked with a blood smear under a microscope. This test involves drawing a small amount of blood from an arm vein.

Bone Marrow Test

A bone marrow test determines how healthy your bone marrow is. Bone marrow is where blood cells are made, including platelets. A biopsy and an aspiration are the two bone marrow tests.

If your bone marrow isn't producing enough blood cells, you might need a bone marrow aspiration. A needle is used to remove a sample of fluid from your bone marrow for this test. Under a microscope, the sample is inspected for faulty cells.

Aspiration is often followed by a bone marrow biopsy. A needle is used to remove bone marrow tissue for this test. Using a microscope, he or she examines the bone marrow to determine how many and what types of cells are present.

Other Blood Tests

Other blood tests may be required if bleeding is suspected. PT and PTT tests may be recommended by your doctor to determine whether your blood clots properly.

An ultrasound of your spleen can also be recommended by your doctor. Ultrasounds produce images of your spleen using sound waves. If your spleen is enlarged, your doctor can detect it with this test.

Medical History

Platelets can be affected by a variety of factors, including,

  • Your medication regimen, over-the-counter products and herbal remedies, and whether or not you consume beverages containing quinine. 

  • What you normally eat and drink, including how much alcohol you consume.

  • You will be asked about your risk for AIDS, including sexual partners, blood transfusions, exposure to infectious blood or body fluids, and intravenous (IV) drugs.

  • Having a low platelet count history in the family.

Physical Examination

When your doctor examines you, they will look for signs of bleeding, such as spots or bruises on the skin. A doctor will also look for signs of a spleen or liver enlargement in your abdomen. Fever and other signs of infection will also be checked. Book an appointment at the best hemato oncology hospital in bangalore.

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