Thalassemia major / Trait

Thalassemia Trait in Yeshwanthpur, Bangalore

About Thalassemia Trait

Thalassemia is a genetic blood illness which makes your body produce less haemoglobin than usual. Red blood cells can carry oxygen because of haemoglobin, and less haemoglobin means less blood production. Anaemia caused by Thalassemia can make you feel exhausted.

You may not require therapy if you suffer from mild Thalassemia. However, more severe conditions could need frequent blood transfusions. You can combat weariness and fatigue by choosing a nutritious diet and regular exercise. Thalassemia treatment in Yeshwanthpur, Bangalore is available at Manipal Hospitals.

What leads to Thalassemia?

Two alpha globin chains and two beta globin chains make up the four protein chains that build haemoglobin. Both the alpha and beta chains are made up of genes that were inherited from your parents. Consider these genes as the "coding" or programming for each chain, which in turn regulates your haemoglobin. You will develop Thalassemia if one or more of these genes are damaged or absent.

  • Two genes from each parent make up each of the four alpha globin protein chains.

  • Each parent contributes one gene to the beta-globin protein chain.

Whether you have Thalassemia in your alpha or beta chains is determined by a genetic abnormality. Your condition's severity will depend on how bad the flaw is.

Symptoms of Thalassemia


If you are missing one alpha gene, you probably won't experience any symptoms. You might not have any symptoms if you lack two alpha genes or one beta gene. You can also be experiencing moderate anaemia symptoms like weariness. Book an appointment with us today.

Moderate to mild symptoms

Beta thalassemia intermedia could result in minor anaemic symptoms or the following signs,

  • Issues with growth.

  • Prolonged puberty.

  • Anomalies of the bones, such as osteoporosis.

  • Increased spleen size

Severe symptoms

Three alpha genes are missing in haemoglobin H disorder, which frequently results in severe lifelong anaemia and anaemia signs from birth. By the age of two, severe anaemia symptoms caused by beta thalassemia major (Cooley's anaemia) are frequently present.

Severe anaemia symptoms include those linked to mild to moderate illness. Additional signs could be,

  • sluggish appetite

  • skin that is yellow or pale (jaundice)

  • dark-coloured or tea-coloured urine

  • irregular facial bone structure

Treatment for Thalassemia

Throughout their lifetimes, people with thalassemia major or other severe kinds will require specialised care.

The primary therapies are,

  • Regular blood transfusions are used to manage and prevent anaemia; in severe cases, roughly once a month is required.

  • Chelation therapy is a medical procedure used to treat persons with Thalassemia who accumulate too much iron in their bodies due to frequent blood transfusions; this condition necessitates medical attention.

You can maintain your health by eating well, exercising frequently, and abstaining from alcohol and tobacco use.

What kind of ongoing care is required by patients suffering from Thalassemia?

Regular full blood tests and blood iron testing are required. Annual tests for liver and heart function may be advised by your doctor. Additionally, they might advise viral infection tests. An annual test for liver iron excess is also required.

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