The Department of Ophthalmology at Manipal Hospitals is a complete eye care centre which provides medical and surgical treatments for all kinds of ailments related to the eye. Much sought after, it draws patients from all over the country as well as patients from Australia, The Maldives, Canada, the Middle East and more. On duty is a team of highly skilled ophthalmologists who use the latest cutting edge technology to provide the best possible eye care in the country. The centre has 3 dedicated operation theatres and an ultra-modern day care unit for the convenience of its patients. It is up-to-date with the latest diagnostic equipment such as the corneal topograph, pachymeter, MEL-80 Carl Zeiss Exciemer laser, PDT, digital imaging system and many more.

The centre is known for the wide range of surgeries that it conducts with an expert touch, such as refractive surgery, cataract surgery, retinoplasty and corneal transplants. Laser procedures for myopia such as LASIK and others like endoscopic DCR, IOL implants, Orbitomies and stem cell transplants are also routinely conducted here. In addition, the centre specialises in Paediatric Ophthalmology, a stream of opthalmology that addresses a range of ocular problems in children. Squints, congenital cataract defects, lazy eye, astigmatism and various other problems are dealt with by surgery or day procedures on a regular basis.